購物車
幫助
021-54845833/15800441009
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Background: |
TNIP3, which called LIND, that was upregulated in monocytes infected with Listeria monocytogenes. The predicted 325-amino acid protein contains 3 coiled-coil domains and is most likely localized to the nucleus. Binds to zinc finger protein TNFAIP3 and inhibits NF-kappa-B activation induced by tumor necrosis factor, Toll-like receptor 4 (TLR4), interleukin-1 and 12-O-tetradecanoylphorbol-13-acetate. Overexpression inhibits NF-kappa-B-dependent gene expression in response to lipopolysaccharide at a level downstream of TRAF6 and upstream of IKBKB. NF-kappa-B inhibition is independent of TNFAIP3 binding. |
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Applications: |
ELISA, WB |
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Name of antibody: |
TNIP3 |
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Immunogen: |
Synthetic peptide of human TNIP3 |
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Full name: |
TNFAIP3 interacting protein 3 |
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Synonyms： |
LIND; ABIN-3 |
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SwissProt: |
Q96KP6 |
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ELISA Recommended dilution: |
1000-2000 |
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WB Predicted band size: |
39 kDa |
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WB Positive control: |
Mouse brain tissue |
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WB Recommended dilution: |
200-1000 |
