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021-54845833/15800441009
中文名稱： 兔抗NIPBL多克隆抗體
英文名稱： Anti-NIPBL rabbit polyclonal antibody
別 名： NIPBL, cohesin loading factor; CDLS; IDN3; Scc2; CDLS1; IDN3-B
相關類別： 一抗
儲 存： 冷凍（-20℃）
宿 主： Rabbit
抗 原： NIPBL
反應種屬： Human, Mouse
標 記 物： Unconjugate
克隆類型： rabbit polyclonal
技術規格
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Background: |
This gene encodes the homolog of the Drosophila melanogaster Nipped-B gene product and fungal Scc2-type sister chromatid cohesion proteins. The Drosophila protein facilitates enhancer-promoter communication of remote enhancers and plays a role in developmental regulation. It is also homologous to a family of chromosomal adherins with broad roles in sister chromatid cohesion, chromosome condensation, and DNA repair. The human protein has a bipartite nuclear targeting sequence and a putative HEAT repeat. Condensins, cohesins and other complexes with chromosome-related functions also contain HEAT repeats. Mutations in this gene result in Cornelia de Lange syndrome, a disorder characterized by dysmorphic facial features, growth delay, limb reduction defects, and cognitive disability. Two transcript variants encoding different isoforms have been found for this gene. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
NIPBL |
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Immunogen: |
Fusion protein of human NIPBL |
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Full name: |
NIPBL, cohesin loading factor |
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Synonyms: |
CDLS; IDN3; Scc2; CDLS1; IDN3-B |
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SwissProt: |
Q6KC79 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human thyroid cancer |
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IHC Recommend dilution: |
50-200 |
