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Background: |
This gene is a member of the echinoderm microtubule associated protein-like family. The encoded WD-repeat protein may be involved in microtubule formation. Abnormal fusion of parts of this gene with portions of the anaplastic lymphoma receptor tyrosine kinase gene, which generates EML4-ALK fusion transcripts, is one of the primary mutations associated with non-small cell lung cancer. Alternative splicing of this gene results in two transcript variants. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
EML4 |
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Immunogen: |
Synthetic peptide of human EML4 |
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Full name: |
echinoderm microtubule associated protein like 4 |
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Synonyms: |
C2orf2; ELP120; EMAP-4; EMAPL4; ROPP120 |
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SwissProt: |
Q9HC35 |
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ELISA Recommended dilution: |
2000-5000 |
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IHC positive control: |
Human gastric cancer and human esophagus cancer |
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IHC Recommend dilution: |
25-100 |

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