購(gòu)物車
幫助
021-54845833/15800441009
中文名稱： 兔抗RNF111多克隆抗體
英文名稱： Anti-RNF111 rabbit polyclonal antibody
別 名： ring finger protein 111; ARK; hRNF111
相關(guān)類別： 一抗
儲(chǔ) 存： 冷凍（-20℃）
宿 主： Rabbit
抗 原： RNF111
反應(yīng)種屬： Human, Mouse
標(biāo) 記 物： Unconjugate
克隆類型： rabbit polyclonal
技術(shù)規(guī)格
Background:
The protein encoded by this gene is a nuclear RING-domain containing E3 ubiquitin ligase. This protein interacts with the transforming growth factor (TGF) -beta/NODAL signaling pathway by promoting the ubiquitination and proteosomal degradation of negative regulators, like SMAD proteins, and thereby enhances TGF-beta target-gene transcription. As a modulator of the nodal signaling cascade, this gene plays a critical role in the induction of mesoderm during embryonic development. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.
Applications:
ELISA, WB, IHC
Name of antibody:
RNF111
Immunogen:
Fusion protein of human RNF111
Full name:
ring finger protein 111
Synonyms:
ARK; hRNF111
SwissProt:
Q6ZNA4
ELISA Recommended dilution:
5000-10000
IHC positive control:
Human gastric cancer
IHC Recommend dilution:
50-300
WB Predicted band size:
109 kDa
WB Positive control:
TM4 cell lysate
WB Recommended dilution:
200-1000
