購物車
幫助
021-54845833/15800441009
中文名稱： 兔抗PTPRJ多克隆抗體
英文名稱： Anti-PTPRJ rabbit polyclonal antibody
別 名： DEP1, SCC1, CD148, HPTPeta, R-PTP-ETA
相關(guān)類別： 一抗
儲 存： 冷凍（-20℃）
宿 主： Rabbit
抗 原： PTPRJ
反應(yīng)種屬： Human, Mouse
標(biāo) 記 物： Unconjugate
克隆類型：rabbit polyclonal
技術(shù)規(guī)格
|
Background: |
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes, including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region containing five fibronectin type III repeats, a single transmembrane region, and a single intracytoplasmic catalytic domain, and thus represents a receptor-type PTP. This protein is present in all hematopoietic lineages, and was shown to negatively regulate T cell receptor signaling possibly through interfering with the phosphorylation of Phospholipase C Gamma 1 and Linker for Activation of T Cells. This protein can also dephosphorylate the PDGF beta receptor, and may be involved in UV-induced signal transduction. Multiple transcript variants encoding different isoforms have been found for this gene. |
|
Applications: |
ELISA, IHC |
|
Name of antibody: |
PTPRJ |
|
Immunogen: |
Synthetic peptide of human PTPRJ |
|
Full name: |
Protein tyrosine phosphatase, receptor type, J |
|
Synonyms： |
DEP1, SCC1, CD148, HPTPeta, R-PTP-ETA |
|
SwissProt: |
Q12913 |
|
ELISA Recommended dilution: |
1000-5000 |
|
IHC positive control: |
Human breast cancer and Human liver cancer |
|
IHC Recommend dilution: |
25-100 |
