購物車
幫助
021-54845833/15800441009
中文名稱 : 兔抗MSRB1多克隆抗體
英文名稱 : Anti-MSRB1 rabbit polyclonal antibody
別 名 : methionine sulfoxide reductase B1; SELR; SELX; SepR; SEPX1; HSPC270
儲(chǔ) 存 : 冷凍（-20℃）
宿 主 : Rabbit
抗 原 : MSRB1
相關(guān)類別 : 一抗
反應(yīng)種屬 : Human
標(biāo) 記 物 : Unconjugate
克隆類型 : rabbit polyclonal
技術(shù)規(guī)格
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Background: |
The protein encoded by this gene belongs to the methionine-R-sulfoxide reductase B (MsrB) family. Members of this family function as repair enzymes that protect proteins from oxidative stress by catalyzing the reduction of methionine-R-sulfoxides to methionines. This protein is highly expressed in liver and kidney, and is localized to the nucleus and cytosol. It is the only member of the MsrB family that is a selenoprotein, containing a selenocysteine (Sec) residue at its active site. It also has the highest methionine-R-sulfoxide reductase activity compared to other members containing cysteine in place of Sec. Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
MSRB1 |
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Immunogen: |
Synthetic peptide of human MSRB1 |
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Full name: |
methionine sulfoxide reductase B1 |
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Synonyms: |
SELR; SELX; SepR; SEPX1; HSPC270 |
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SwissProt: |
Q9NZV6 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human colorectal cancer and Human cervical cancer |
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IHC Recommend dilution: |
25-100 |
