購物車
幫助
021-54845833/15800441009
中文名稱： 兔抗YTHDF1多克隆抗體
|
Background: |
YTHDF1, also designated Dermatomyositis associated with cancer putative autoantigen 1 (DACA-1), is a 559 amino acid protein that contains one YTH domain, which is a potential RNA binding domain. Specifically recognizes and binds N6-methyladenosine (m6A)-containing mRNAs, and promotes mRNA translation efficiency (PubMed:24284625, PubMed:26046440, PubMed:26318451). M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in the efficiency of mRNA splicing, processing and stability (PubMed:24284625). Acts as a regulator of mRNA translation efficiency: promotes ribosome loading to m6A-containing mRNAs and interacts with translation initiation factors eIF3 (EIF3A or EIF3B) to facilitate translation initiation (PubMed:26046440). |
|
Applications: |
ELISA, IHC |
|
Name of antibody: |
YTHDF1 |
|
Immunogen: |
Synthetic peptide of human YTHDF1 |
|
Full name: |
YTH N6-methyladenosine RNA binding protein 1 |
|
Synonyms: |
C20orf21 |
|
SwissProt: |
Q9BYJ9 |
|
ELISA Recommended dilution: |
5000-10000 |
|
IHC positive control: |
Human cervical cancer |
|
IHC Recommend dilution: |
40-200 |
