購物車
幫助
021-54845833/15800441009
中文名稱： CARD11抗原（重組蛋白）
英文名稱： CARD11 Antigen (Recombinant Protein)
別 名： PPBL; BENTA; BIMP3; IMD11; CARMA1
儲 存： 冷凍（-20℃）
相關類別： 抗原
概 述：
|
Fusion protein corresponding to a region derived from 300-502 amino acids of human CARD11 |
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Full name: |
caspase recruitment domain family, member 11 |
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Synonyms: |
PPBL; BENTA; BIMP3; IMD11; CARMA1 |
|
Swissprot: |
Q9BXL7 |
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Gene Accession: |
BC111719 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. |
