Name: AFP抗原（重組蛋白）
Brand: 通蔚生物

中文名稱： AFP抗原（重組蛋白）

英文名稱： AFP Antigen (Recombinant Protein)

相關類別：抗原

儲存： 冷凍（-20℃）避光

概述

Fusion protein corresponding to a region derived from 261-609 amino acids of human AFP

技術規格

Full name:	Alpha-fetoprotein
Synonyms:	FETA, HPAFP
Swissprot:	P02771
Gene Accession:	BC027881
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.

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