Name: BMP4抗原（重組蛋白）
Brand: 通蔚生物

中文名稱：BMP4抗原（重組蛋白）

英文名稱：BMP4 Antigen (Recombinant Protein)

儲(chǔ) 存：冷凍（-20℃）

相關(guān)類別：抗原

概述

Fusion protein corresponding to a region derived from 293-408 amino acids of human BMP4

技術(shù)規(guī)格

Full name:	bone morphogenetic protein 4
Synonyms:	ZYME; BMP2B; OFC11; BMP2B1; MCOPS6
Swissprot:	P12644
Gene Accession:	BC020546
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates heart development and adipogenesis. Mutations in this gene are associated with orofacial cleft and microphthalmia in human patients. The encoded protein may also be involved in the pathology of multiple cardiovascular diseases and human cancers.

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