購物車
幫助
021-54845833/15800441009
中文名稱：CRTAM抗原（重組蛋白）
英文名稱：CRTAM Antigen (Recombinant Protein)
儲 存：冷凍（-20℃）
相關類別：抗原
概述
|
Fusion protein corresponding to a region derived from 38-287 amino acids of human CRTAM |
技術規格
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Full name: |
cytotoxic and regulatory T cell molecule |
|
Synonyms: |
CD355 |
|
Swissprot: |
O95727 |
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Gene Accession: |
BC070266 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
Class-I MHC-restricted T cell associated molecule (CRTAM) is a receptor that is primarily expressed on activated cytotoxic lymphocytes, where it may play a role in their adhesion, interaction or migration. It is one of the most highly expressed surface markers detected on activated human NK T cells and CD8 T cells, suggesting its use as a diagnostic tool in various human viral and autoimmune diseases. CRTAM binds nectin-like protein 2 (necl2), which is involved in IL-22 expression regulation. This Necl2/CRTAM molecular pair may regulate cell/cell interactions and may play a role in neuronal interactions. CRTAM is also highly expressed in Purkinje neurons in the cerebellum. |
