購物車
幫助
021-54845833/15800441009
英文名稱： NDUFA12 Antigen (Recombinant Protein)
概 述
|
Full name: |
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12 |
|
Synonyms: |
B17.2; DAP13 |
|
Swissprot: |
Q9UI09 |
|
Gene Accession: |
BC005936 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background: |
This gene encodes a protein which is part of mitochondrial complex 1, part of the oxidative phosphorylation system in mitochondria. Complex 1 transfers electrons to ubiquinone from NADH which establishes a proton gradient for the generation of ATP. Mutations in this gene are associated with Leigh syndrome due to mitochondrial complex 1 deficiency. Pseudogenes of this gene are located on chromosomes 5 and 13. Alternative splicing results in multiple transcript variants. |
