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中文名稱：CASP6抗原（重組蛋白）
英文名稱：CASP6 Antigen (Recombinant Protein)
儲 存：冷凍（-20℃）
相關類別：抗原
概述
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Fusion protein corresponding to a region derived from 66-221 amino acids of human CASP6 |
技術規格
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Full name: |
Caspase 6, apoptosis-related cysteine peptidase |
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Synonyms: |
MCH2 |
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Swissprot: |
P55212 |
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Gene Accession: |
BC000305 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of this gene results in two transcript variants that encode different isoforms. |
