購(gòu)物車
幫助
021-54845833/15800441009
中文名稱：小鼠抗FBXO22單克隆抗體
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Background: |
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and, as a transcriptional target of the tumor protein p53, is thought to be involved in degradation of specific proteins in response to p53 induction. Alternative splicing results in multiple transcript variants. |
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Applications: |
WB |
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Name of antibody: |
FBXO22 |
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Immunogen: |
Fusion protein of human FBXO22 |
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Full name: |
F-box protein 22 |
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Synonyms: |
FBX22; FISTC1 |
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SwissProt: |
Q8NEZ5 |
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WB Predicted band size: |
45 KD |
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WB Positive control: |
A549, HepG2 cell, Mouse heart tissue lysates |
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WB Recommended dilution: |
500-2000 |
