購物車
幫助
021-54845833/15800441009
中文名稱：小鼠抗CHD3(C-term)單克隆抗體
|
Background: |
This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described. |
|
Applications: |
WB, IF, IP |
|
Name of antibody: |
CHD3(C-term) |
|
Immunogen: |
Fusion protein of human CHD3 |
|
Full name: |
chromodomain helicase DNA binding protein 3 |
|
Synonyms: |
ZFH; Mi-2a; Mi2-ALPHA |
|
SwissProt: |
Q12873 |
|
WB Predicted band size: |
227 kDa |
|
WB Positive control: |
NTERA2, 3T3, C6, K562 and Hela cell lysates |
|
WB Recommended dilution: |
1000-5000 |
|
IF positive control: |
Hela cells |
|
IF Recommend dilution: |
200-400 |
