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021-54845833/15800441009
中文名稱：兔抗CGAS多克隆抗體
英文名稱： Anti-CGAS rabbit polyclonal antibody
別 名： cyclic GMP-AMP synthase; MB21D1; h-cGAS; C6orf150
相關(guān)類別： 一抗
儲 存： 冷凍（-20℃）
抗 原： CGAS
宿 主： Rabbit
反應(yīng)種屬： Human
標(biāo) 記 物： Unconjugate
克隆類型： rabbit polyclonal
技術(shù)規(guī)格
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Background: |
cGAS (cyclic GMP-AMP synthase), also known as MB21D1 (Mab-21 domain containing 1), h-cGAS or C6orf150, is a 522 amino acid cytoplasmic nucleotidyltransferase that catalyzes the formation of cyclic GMP-AMP (cGAMP) from ATP and GTP. cGAS is suggested to have antiviral activity by acting as a key cytosolic DNA sensor. cGAS binds to cytosolic DNA, which leads to cGAMP synthesis and activation of TMEM173, thereby trigger type-I interferon production. Expressed in monocytic cell line THP1, cGAS exists as two alternatively spliced isoforms and is encoded by a gene located on human chromosome 6q13. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
CGAS |
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Immunogen: |
Synthetic peptide of human CGAS |
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Full name: |
cyclic GMP-AMP synthase |
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Synonyms: |
MB21D1; h-cGAS; C6orf150 |
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SwissProt: |
Q8N884 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human liver cancer |
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IHC Recommend dilution: |
20-100 |
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WB Predicted band size: |
59 kDa |
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WB Positive control: |
HT-29 and Lovo cell lysates |
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WB Recommended dilution: |
500-2000 |
