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  • 兔抗ZYX多克隆抗體

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    • 品牌 : 通蔚生物
    • 目錄號 : TW6024
    • 應用 : 僅限于科研使用
    • 貨期 : 現貨
    • 規格 :100ul/200ul/25ul
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中文名稱: 兔抗ZYX多克隆抗體

英文名稱: Anti-ZYX rabbit polyclonal antibody

別       名: ESP-2; HED-2

抗       原: ZYX

儲       存: 冷凍(-20℃)

宿       主: Rabbit

相關類別: 一抗

反應種屬: Human, Mouse

標 記  物: Unconjugate

克隆類型: rabbit polyclonal

技術規格

Background:

Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles. Alternative splicing results in multiple transcript variants that encode the same isoform.

Applications:

ELISA, WB, IHC

Name of antibody:

ZYX

Immunogen:

Fusion protein of human ZYX

Full name:

zyxin

Synonyms:

ESP-2; HED-2

SwissProt:

Q15942

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human colorectal cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

61 kDa

WB Positive control:

293T cell lysate

WB Recommended dilution:

200-1000





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