Name: U2AF2 抗原（重組蛋白）
Brand: 通蔚生物

中文名稱： U2AF2 抗原（重組蛋白）

英文名稱： U2AF2 Antigen (Recombinant Protein)

別名： U2 small nuclear RNA auxiliary factor 2; U2AF65

相關類別：抗原

儲存： 冷凍（-20℃）

概述

Fusion protein corresponding to a region derived from 272-471 amino acids of human U2AF2

技術規格

Full name:	U2 small nuclear RNA auxiliary factor 2
Synonyms:	U2AF65
Swissprot:	P26368
Gene Accession:	BC008740
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	U2 auxiliary factor (U2AF), comprised of a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. This gene encodes the U2AF large subunit which contains a sequence-specific RNA-binding region with 3 RNA recognition motifs and an Arg/Ser-rich domain necessary for splicing. The large subunit binds to the polypyrimidine tract of introns early during spliceosome assembly. Multiple transcript variants have been detected for this gene, but the full-length natures of only two have been determined to date.

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