購(gòu)物車(chē)
幫助
021-54845833/15800441009
中文名稱(chēng)：兔抗CDKN2C多克隆抗體
英文名稱(chēng)： Anti-CDKN2C rabbit polyclonal antibody
別 名： p18; INK4C; p18-INK4C
相關(guān)類(lèi)別： 一抗
抗 原： CDKN2C
宿 主： Rabbit
反應(yīng)種屬： Human, Mouse
標(biāo) 記 物：Unconjugate
克隆類(lèi)型： rabbit polyclonal
技術(shù)規(guī)格
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Background: |
The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to interact with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. Ectopic expression of this gene was shown to suppress the growth of human cells in a manner that appears to correlate with the presence of a wild-type RB1 function. Studies in the knockout mice suggested the roles of this gene in regulating spermatogenesis, as well as in suppressing tumorigenesis. Two alternatively spliced transcript variants of this gene, which encode an identical protein, have been reported |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
CDKN2C |
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Immunogen: |
Fusion protein of human CDKN2C |
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Full name: |
cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) |
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Synonyms： |
p18; INK4C; p18-INK4C |
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SwissProt: |
P42773 |
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ELISA Recommended dilution: |
1000-2000 |
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IHC positive control: |
Human thyroid cancer and human brain |
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IHC Recommend dilution: |
25-100 |
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WB Predicted band size: |
18 kDa |
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WB Positive control: |
Raji cells |
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WB Recommended dilution: |
200-1000 |
