購(gòu)物車
幫助
021-54845833/15800441009
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Background: |
Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
VCL |
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Immunogen: |
Synthetic peptide of human VCL |
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Full name: |
vinculin |
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Synonyms： |
MVCL, CMD1W, CMH15 |
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SwissProt: |
P18206 |
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ELISA Recommended dilution: |
5000-240000 |
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IHC positive control: |
Human liver cancer and human lung cancer |
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IHC Recommend dilution: |
25-100 |
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WB Predicted band size: |
123 kDa |
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WB Positive control: |
Hela cells |
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WB Recommended dilution: |
1000-4000 |
