購物車
幫助
021-54845833/15800441009
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Background: |
This translocase is involved in the import and insertion of hydrophobic membrane proteins from the cytoplasm into the mitochondrial inner membrane. The gene is mutated in Mohr-Tranebjaerg syndrome/Deafness Dystonia Syndrome (MTS/DDS) and it is postulated that MTS/DDS is a mitochondrial disease caused by a defective mitochondrial protein import system. Defects in this gene also cause Jensen syndrome; an X-linked disease with opticoacoustic nerve atrophy and muscle weakness. This protein, along with TIMM13, forms a 70 kDa heterohexamer. Alternative splicing results in multiple transcript variants encoding distinct isoforms. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
TIMM8A |
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Immunogen: |
Fusion protein of human TIMM8A |
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Full name: |
translocase of inner mitochondrial membrane 8A |
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Synonyms: |
DDP; MTS; DDP1; DFN1; TIM8 |
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SwissProt: |
O60220 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human cervical cancer |
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IHC Recommend dilution: |
40-200 |
