購物車
幫助
021-54845833/15800441009
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Background: |
The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells in mice, rats, and humans. This receptor possesses a unique extracellular domain containing 2 immunoglobulin-like loops separated by 3 epidermal growth factor-like repeats that are connected to 3 fibronectin type III-like repeats. The ligand for the receptor is angiopoietin-1. Defects in TEK are associated with inherited venous malformations; the TEK signaling pathway appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis. TEK is closely related to the TIE receptor tyrosine kinase. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
TEK |
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Immunogen: |
Synthetic peptide of human TEK |
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Full name: |
TEK tyrosine kinase, endothelial |
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Synonyms： |
TIE2; VMCM; TIE-2; VMCM1; CD202B |
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SwissProt: |
Q02763 |
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ELISA Recommended dilution: |
3000-10000 |
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IHC positive control: |
Human liver cancer and Human thyroid cancer |
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IHC Recommend dilution: |
50-200 |
