購物車
幫助
021-54845833/15800441009
|
Background: |
This gene encodes a member of the suppressor of cytokine signaling (SOCS) family. SOCS family members are cytokine-inducible negative regulators of cytokine receptor signaling via the Janus kinase/signal transducer and activation of transcription pathway (the JAK/STAT pathway). SOCS family proteins interact with major molecules of signaling complexes to block further signal transduction, in part, by proteasomal depletion of receptors or signal-transducing proteins via ubiquitination. The expression of this gene can be induced by a subset of cytokines, including erythropoietin, GM-CSF, IL10, interferon (IFN)-gamma and by cytokine receptors such as growth horomone receptor. |
|
Applications: |
ELISA, IHC |
|
Name of antibody: |
SOCS2 |
|
Immunogen: |
Fusion protein of human SOCS2 |
|
Full name: |
suppressor of cytokine signaling 2 |
|
Synonyms： |
CIS2; SSI2; Cish2; SSI-2; SOCS-2; STATI2 |
|
SwissProt: |
O14508 |
|
ELISA Recommended dilution: |
1000-2000 |
|
IHC positive control: |
Human brain |
|
IHC Recommend dilution: |
25-100 |
