購物車
幫助
021-54845833/15800441009
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Background: |
This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in myogenic growth and differentiation. Translocation of this gene with PAX3 has been associated with alveolar rhabdomyosarcoma. Interacts with LRPPRC. Interacts with RUNX2; the interaction inhibits RUNX2 transcriptional activity and mediates the IGF1/insulin-dependent BGLAP expression in osteoblasts Interacts with PPP2R1A; the interaction regulates the dephosphorylation of FOXO1 at Thr-24 and Ser-256 leading to its nuclear import. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
FOXO1 |
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Immunogen: |
Synthetic peptide of human FOXO1 |
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Full name: |
forkhead box O1 |
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Synonyms： |
FKH1, FKHR, FOXO1A |
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SwissProt: |
Q12778 |
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ELISA Recommended dilution: |
1000-2000 |
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IHC positive control: |
Human thyroid cancer and Human liver cancer |
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IHC Recommend dilution: |
25-100 |
