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021-54845833/15800441009
中文名稱： 兔抗NPR1多克隆抗體
英文名稱： Anti-NPR1 rabbit polyclonal antibody
別 名： ANPa, NPRA, ANPRA, GUC2A, GUCY3A
相關類別： 一抗
儲 存： 冷凍（-20℃）
宿 主： Rabbit
抗 原： NPR1
反應種屬： Human, Mouse, Rat
標 記 物： Unconjugate
克隆類型：rabbit polyclonal
技術規格
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Background: |
Guanylyl cyclases, catalyzing the production of cGMP from GTP, are classified as soluble and membrane forms . The membrane guanylyl cyclases, often termed guanylyl cyclases A through F, form a family of cell-surface receptors with a similar topographic structure: an extracellular ligand-binding domain, a single membrane-spanning domain, and an intracellular region that contains a protein kinase-like domain and a cyclase catalytic domain. GC-A and GC-B function as receptors for natriuretic peptides; they are also referred to as atrial natriuretic peptide receptor A (NPR1) and type B (NPR2; MIM 108961). Also see NPR3 (MIM 108962), which encodes a protein with only the ligand-binding transmembrane and 37-amino acid cytoplasmic domains. NPR1 is a membrane-bound guanylate cyclase that serves as the receptor for both atrial and brain natriuretic peptides (ANP (MIM 108780) and BNP (MIM 600295), respectively). |
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Applications: |
ELISA, IHC |
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Name of antibody: |
NPR1 |
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Immunogen: |
Synthetic peptide of human NPR1 |
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Full name: |
Natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A) |
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Synonyms： |
ANPa, NPRA, ANPRA, GUC2A, GUCY3A |
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SwissProt: |
P16066 |
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ELISA Recommended dilution: |
1000-5000 |
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IHC positive control: |
Human brain and Human gastric cancer |
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IHC Recommend dilution: |
25-100 |
