購(gòu)物車(chē)
幫助
021-54845833/15800441009
中文名稱： 兔抗NELFA多克隆抗體
英文名稱： Anti-NELFA rabbit polyclonal antibody
別 名： WHSC2; NELF-A; P/OKcl.15
相關(guān)類(lèi)別： 一抗
儲(chǔ) 存： 冷凍（-20℃）
宿 主： Rabbit
抗 原： NELFA
反應(yīng)種屬： Human, Mouse
標(biāo) 記 物： Unconjugate
克隆類(lèi)型： rabbit polyclonal
技術(shù)規(guī)格
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Background: |
This gene is expressed ubiquitously with higher levels in fetal than in adult tissues. It encodes a protein sharing 93% sequence identity with the mouse protein. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene is mapped to the 165 kb WHS critical region, and may play a role in the phenotype of the WHS or Pitt-Rogers-Danks syndrome. The encoded protein is found to be capable of reacting with HLA-A2-restricted and tumor-specific cytotoxic T lymphocytes, suggesting a target for use in specific immunotherapy for a large number of cancer patients. This protein has also been shown to be a member of the NELF (negative elongation factor) protein complex that participates in the regulation of RNA polymerase II transcription elongation. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
NELFA |
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Immunogen: |
Fusion protein of human NELFA |
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Full name: |
negative elongation factor complex member A |
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Synonyms: |
WHSC2; NELF-A; P/OKcl.15 |
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SwissProt: |
Q9H3P2 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human thyroid cancer and human esophagus cancer |
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IHC Recommend dilution: |
25-100 |
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WB Predicted band size: |
57 kDa |
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WB Positive control: |
NIH/3T3，RAW264.7 and Hela cell lysates |
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WB Recommended dilution: |
200-1000 |
