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  • 兔抗FBXO32多克隆抗體

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    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW20289
    • 應(yīng)用 : 僅供科研使用
    • 貨期 : 現(xiàn)貨
    • 規(guī)格 :100ul/200ul/25ul
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中文名稱(chēng): 兔抗FBXO32多克隆抗體

英文名稱(chēng): Anti-FBXO32 rabbit polyclonal antibody

別      名: Fbx32; MAFbx

相關(guān)類(lèi)別: 一抗

抗      原: FBXO32

儲(chǔ)      存: 冷凍(-20℃)

宿      主: Rabbit

反應(yīng)種屬: Human, Mouse, Rat

標(biāo)  記 物: Unconjugate

克隆類(lèi)型: rabbit polyclonal

技術(shù)規(guī)格

Background:

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing results in multiple transcript variants encoding different isoforms.

Applications:

ELISA, IHC

Name of antibody:

FBXO32

Immunogen:

Synthetic peptide corresponding to a region derived from 69-82 amino acids of human FBXO32

Full name:

F-box protein 32

Synonyms:

Fbx32; MAFbx

SwissProt:

Q969P5

ELISA Recommended dilution:

5000-10000

IHC Positive control:

Human liver cancer;Human prostate cancer

IHC Recommended dilution:

30-150




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