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021-54845833/15800441009
英文名稱： UBE2D3 Antigen (Recombinant Protein)
別 名： UBC4/5; UBCH5C; E2(17)KB3
儲(chǔ) 存： 冷凍（-20℃）
相關(guān)類別： 抗原
概 述
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Full name: |
ubiquitin conjugating enzyme E2D 3 |
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Synonyms: |
UBC4/5; UBCH5C; E2(17)KB3 |
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Swissprot: |
P61077 |
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Gene Accession: |
BC003395 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase. Multiple spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been determined. |
