Name: THOC7抗原（重組蛋白）
Brand: 通蔚生物

中文名稱(chēng)： THOC7抗原（重組蛋白）

英文名稱(chēng)： THOC7 Antigen (Recombinant Protein)

別名： fSAP24; hTREX30; NIF3L1BP1

儲(chǔ) 存： 冷凍（-20℃）

相關(guān)類(lèi)別：抗原

概述

Full length fusion protein

技術(shù)規(guī)格

Full name:	THO complex 7
Synonyms:	fSAP24; hTREX30; NIF3L1BP1
Swissprot:	Q6I9Y2
Gene Accession:	BC065012
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	Required for efficient export of polyadenylated RNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway. The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production.

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