Name: PDCD6抗原（重組蛋白）
Brand: 通蔚生物

中文名稱： PDCD6抗原（重組蛋白）

英文名稱： PDCD6 Antigen (Recombinant Protein)

別名： ALG-2, PEF1B

儲存： 冷凍（-20℃）

相關(guān)類別：抗原

概述

Full length fusion protein

技術(shù)規(guī)格

Full name:	programmed cell death 6
Synonyms:	ALG-2, PEF1B
Swissprot:	O75340
Gene Accession:	BC012384
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	This gene encodes a calcium-binding protein belonging to the penta-EF-hand protein family. Calcium binding is important for homodimerization and for conformational changes required for binding to other protein partners. This gene product participates in T cell receptor-, Fas-, and glucocorticoid-induced programmed cell death. In mice deficient for this gene product, however, apoptosis was not blocked suggesting this gene product is functionally redundant. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is also located on the short arm of chromosome 5.

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