Name: TLE6 抗原（重組蛋白）
Brand: 通蔚生物

中文名稱：TLE6 抗原（重組蛋白）

英文名稱： TLE6 Antigen (Recombinant Protein)

別名： transducin like enhancer of split 6; GRG6; PREMBL

儲存： 冷凍（-20℃）

相關類別： 抗原

概述：

Fusion protein corresponding to a region derived from 373-572 amino acids of human TLE6

技術規格：

Full name:	transducin like enhancer of split 6
Synonyms:	GRG6; PREMBL
Swissprot:	Q9H808
Gene Accession:	BC020206
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	This gene encodes a member of the Groucho/ transducin-like Enhancer of split family of transcriptional co-repressors. The encoded protein is a component of the mammalian subcortical maternal complex, which is required for preimplantation development. In mouse, knock out of this gene results in cleavage-stage embryonic arrest resulting from defective cytoplasmic F-actin meshwork formation and asymmetric cell division. In human, an allelic variant in this gene is associated with preimplantation embryonic lethality. Alternative splicing results in multiple transcript variants.

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