購物車
幫助
021-54845833/15800441009
中文名稱：SETMAR抗原（重組蛋白）
英文名稱： SETMAR Antigen (Recombinant Protein)
別 名： Mar1; METNASE
儲 存： 冷凍（-20℃）
相關類別： 抗原
概 述：
|
Fusion protein corresponding to a region derived from 14-213 amino acids of human SETMAR |
|
Full name: |
SET domain and mariner transposase fusion gene |
|
Synonyms: |
Mar1; METNASE |
|
Swissprot: |
Q53H47 |
|
Gene Accession: |
BC011635 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background: |
This gene encodes a fusion protein that contains an N-terminal histone-lysine N-methyltransferase domain and a C-terminal mariner transposase domain. The encoded protein binds DNA and functions in DNA repair activities including non-homologous end joining and double strand break repair. The SET domain portion of this protein specifically methylates histone H3 lysines 4 and 36. This gene exists as a fusion gene only in anthropoid primates, other organisms lack mariner transposase domain. Alternate splicing results in multiple transcript variants. |
