購物車
幫助
021-54845833/15800441009
中文名稱：RFX6抗原（重組蛋白）
英文名稱： RFX6 Antigen (Recombinant Protein)
別 名： MTFS; MTCHRS; RFXDC1; dJ955L16.1
儲 存： 冷凍（-20℃）
相關類別： 抗原
概 述：
|
Fusion protein corresponding to a region derived from 729-928 amino acids of human RFX6 |
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Full name: |
regulatory factor X6 |
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Synonyms: |
MTFS; MTCHRS; RFXDC1; dJ955L16.1 |
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Swissprot: |
Q8HWS3 |
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Gene Accession: |
BC039248 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
The nuclear protein encoded by this gene is a member of the regulatory factor X (RFX) family of transcription factors. Studies in mice suggest that this gene is specifically required for the differentiation of islet cells for the production of insulin, but not for the differentiation of pancreatic polypeptide-producing cells. It regulates the transcription factors involved in beta-cell maturation and function, thus, restricting the expression of the beta-cell differentiation and specification genes. Mutations in this gene are associated with Mitchell-Riley syndrome, which is characterized by neonatal diabetes with pancreatic hypoplasia, duodenal and jejunal atresia, and gall bladder agenesis. |
