購物車
幫助
021-54845833/15800441009
中文名稱： 兔抗MECP2多克隆抗體
英文名稱： Anti-MECP2 rabbit polyclonal antibody
別 名： RS; RTS; RTT; PPMX; MRX16; MRX79; MRXSL; AUTSX3; MRXS13
相關(guān)類別： 一抗
儲 存： 冷凍（-20℃）
宿 主： Rabbit
抗 原： MECP2
反應(yīng)種屬： Human, Mouse, Rat
標(biāo) 記 物： Unconjugate
克隆類型： rabbit polyclonal
技術(shù)規(guī)格
|
Background: |
DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. In contrast to other MBD family members, MECP2 is X-linked and subject to X inactivation. MECP2 is dispensible in stem cells, but is essential for embryonic development. |
|
Applications: |
ELISA, WB, IHC |
|
Name of antibody: |
MECP2 |
|
Immunogen: |
Fusion protein of human MECP2 |
|
Full name: |
methyl CpG binding protein 2 |
|
Synonyms： |
RS; RTS; RTT; PPMX; MRX16; MRX79; MRXSL; AUTSX3; MRXS13 |
|
SwissProt: |
P51608 |
|
ELISA Recommended dilution: |
1000-2000 |
|
IHC positive control: |
Human esophagus cancer and Human brain |
|
IHC Recommend dilution: |
100-300 |
|
WB Predicted band size: |
52 kDa |
|
WB Positive control: |
Mouse lung tissue |
|
WB Recommended dilution: |
200-1000 |
