購(gòu)物車(chē)
幫助
021-54845833/15800441009
中文名稱： 兔抗MCM3AP多克隆抗體
英文名稱： Anti-MCM3AP rabbit polyclonal antibody
別 名： GANP; SAC3; MAP80
相關(guān)類別： 一抗
儲(chǔ) 存： 冷凍（-20℃）
抗 原： MCM3AP
宿 主： Rabbit
反應(yīng)種屬： Human
標(biāo) 記 物： Unconjugate
克隆類型： rabbit polyclonal
技術(shù)規(guī)格
|
Background: |
The minichromosome maintenance protein 3 (MCM3) is one of the MCM proteins essential for the initiation of DNA replication. The protein encoded by this gene is a MCM3 binding protein. It was reported to have phosphorylation-dependent DNA-primase activity, which was up-regulated in antigen immunization induced germinal center. This protein was demonstrated to be an acetyltransferase that acetylates MCM3 and plays a role in DNA replication. The mutagenesis of a nuclear localization signal of MCM3 affects the binding of this protein with MCM3, suggesting that this protein may also facilitate MCM3 nuclear localization. This gene is expressed in the brain or in neuronal tissue. An allelic variant encoding amino acid Lys at 915, instead of conserved Glu, has been identified in patients with mild intellectual disability. |
|
Applications: |
ELISA, WB, IHC |
|
Name of antibody: |
MCM3AP |
|
Immunogen: |
Fusion protein of human MCM3AP |
|
Full name: |
minichromosome maintenance complex component 3 associated protein |
|
Synonyms： |
GANP; SAC3; MAP80 |
|
SwissProt: |
O60318 |
|
ELISA Recommended dilution: |
2000-5000 |
|
IHC positive control: |
Human colon cancer and human thyroid cancer |
|
IHC Recommend dilution: |
50-200 |
|
WB Predicted band size: |
218 kDa |
|
WB Positive control: |
Hela and 293T cells |
|
WB Recommended dilution: |
200-1000 |
