購物車
幫助
021-54845833/15800441009
中文名稱：MAP4K2抗原（重組蛋白）
英文名稱： MAP4K2 Antigen (Recombinant Protein)
別 名： GCK; BL44; RAB8IP
儲 存： 冷凍（-20℃）
相關類別： 抗原
概 述：
|
Fusion protein corresponding to C terminal 250 amino acids of human MAP4K2 |
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Full name: |
mitogen-activated protein kinase kinase kinase kinase 2 |
|
Synonyms: |
GCK; BL44; RAB8IP |
|
Swissprot: |
Q12851 |
|
Gene Accession: |
BC047865 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
The protein encoded by this gene is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. This kinase can be activated by TNF-alpha, and has been shown to specifically activate MAP kinases. This kinase is also found to interact with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1/MEKK1. |
