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021-54845833/15800441009
中文名稱： 兔抗MAPK10多克隆抗體
英文名稱： Anti-MAPK10 rabbit polyclonal antibody
別 名： JNK3, JNK3A, PRKM10, SAPK1b, p493F12, p54bSAPK
相關類別： 一抗
儲 存： 冷凍（-20℃）
宿 主： Rabbit
抗 原： MAPK10
反應種屬： Human, Mouse, Rat
標 記 物： Unconjugate
克隆類型： rabbit polyclonal
技術規格
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Background: |
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This protein is a neuronal-specific form of c-Jun N-terminal kinases (JNKs). Through its phosphorylation and nuclear localization, this kinase plays regulatory roles in the signaling pathways during neuronal apoptosis. Beta-arrestin 2, a receptor-regulated MAP kinase scaffold protein, is found to interact with, and stimulate the phosphorylation of this kinase by MAP kinase kinase 4 (MKK4). Cyclin-dependent kianse 5 can phosphorylate, and inhibit the activity of this kinase, which may be important in preventing neuronal apoptosis. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
MAPK10 |
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Immunogen: |
Synthetic peptide of human MAPK10 |
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Full name: |
mitogen-activated protein kinase 10 |
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Synonyms： |
JNK3, JNK3A, PRKM10, SAPK1b, p493F12, p54bSAPK |
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SwissProt: |
P53779 |
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ELISA Recommended dilution: |
1000-5000 |
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IHC positive control: |
Human breast cancer |
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IHC Recommend dilution: |
5-20 |
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WB Predicted band size: |
53 kDa |
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WB Positive control: |
293T cells |
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WB Recommended dilution: |
500-2000 |
