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021-54845833/15800441009
中文名稱： GLIPR1抗原（重組蛋白）
英文名稱： GLIPR1 Antigen (Recombinant Protein)
別 名： GLIPR; RTVP1; CRISP7
儲 存： 冷凍（-20℃）
相關類別： 抗原
概 述：
|
Fusion protein corresponding to a region derived from 22-230 amino acids of human GLIPR1 |
技術規格：
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Full name: |
GLI pathogenesis-related 1 |
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Synonyms: |
GLIPR; RTVP1; CRISP7 |
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Swissprot: |
P48060 |
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Gene Accession: |
BC012510 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes a protein with similarity to both the pathogenesis-related protein (PR) superfamily and the cysteine-rich secretory protein (CRISP) family. Increased expression of this gene is associated with myelomocytic differentiation in macrophage and decreased expression of this gene through gene methylation is associated with prostate cancer. The protein has proapoptotic activities in prostate and bladder cancer cells. This gene is a member of a cluster on chromosome 12 containing two other similar genes. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. |
