Name: OCLN抗原（重組蛋白）
Brand: 通蔚生物

中文名稱： OCLN抗原（重組蛋白）

英文名稱： OCLN Antigen (Recombinant Protein)

別名： BLCPMG

儲(chǔ) 存： 冷凍（-20℃）

相關(guān)類別：抗原

概述

Fusion protein corresponding to a region derived from 266-522 amino acids of human OCLN

技術(shù)規(guī)格

Full name:	Occludin
Synonyms:	BLCPMG
Swissprot:	Q16625
Gene Accession:	BC029886
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	This gene encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band-like calcification with simplified gyration and polymicrogyria (BLC-PMG), an autosomal recessive neurologic disorder that is also known as pseudo-TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene is present 1.5 Mb downstream on the q arm of chromosome 5.

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