Name: KIF3A抗原（重組蛋白）
Brand: 通蔚生物

中文名稱： KIF3A抗原（重組蛋白）

英文名稱： KIF3A Antigen (Recombinant Protein)

別名： FLA10; KLP-20

儲(chǔ) 存： 冷凍（-20℃）

相關(guān)類別：抗原

概述

Fusion protein corresponding to a region derived from 355-590 amino acids of human KIF3A

技術(shù)規(guī)格

Full name:	kinesin family member 3A
Synonyms:	FLA10; KLP-20
Swissprot:	Q9Y496
Gene Accession:	BC045542
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	Kinesin-like protein KIF3A is a protein that in humans is encoded by the KIF3A gene. Members of the heterotrimeric kinesin II family of microtubule associated motors generally contain two different motor subunits from the KIF3 family, which includes KIF3A, B and C. KIF3 isoforms mediate anterograde transport of membrane bound organelles in neurons and melanosomes, transport between the endoplasmic reticulum and the Golgi, and transport of protein complexes within cilia and flagella required for their morphogenesis. KIF3A may influence neurogenesis at the level of embryonic cellular events, where the asymmetry of the genetic control circuit controlling left-right (L-R) axis determination is defined. Loss of KIF3A function in mice photoreceptors causes apoptotic cell death, suggesting that kinesin II mediated transport is required for proper cell fate.

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