Name: ATIC抗原（重組蛋白）
Brand: 通蔚生物

中文名稱： ATIC抗原（重組蛋白）

英文名稱： ATIC Antigen (Recombinant Protein)

別名： 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase; PURH; AICAR; AICARFT; IMPCHASE; HEL-S-70p

儲存： 冷凍（-20℃）

相關類別：抗原

概述

Fusion protein corresponding to C terminal 200 amino acids of human ATIC

技術規格

Full name:	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
Synonyms:	PURH; AICAR; AICARFT; IMPCHASE; HEL-S-70p
Swissprot:	P31939
Gene Accession:	BC008879
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	This gene encodes a bifunctional protein that catalyzes the last two steps of the de novo purine biosynthetic pathway. The N-terminal domain has phosphoribosylaminoimidazolecarboxamide formyltransferase activity, and the C-terminal domain has IMP cyclohydrolase activity. A mutation in this gene results in AICA-ribosiduria.

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