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Background: |
This gene encodes a member of the small C-terminal domain phosphatase (SCP) family of nuclear phosphatases. These proteins play a role in transcriptional regulation through specific dephosphorylation of phosphoserine 5 within tandem heptapeptide repeats of the C-terminal domain of RNA polymerase II. The encoded protein plays a role in neuronal gene silencing in non-neuronal cells, and may also inhibit osteoblast differentiation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
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Applications: |
WB, IHC |
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Name of antibody: |
CTDSP1 |
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Immunogen: |
Synthesized peptide derived from N-terminal of human CTDSP1. |
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Full name: |
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 |
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Synonyms: |
NIF3; SCP1; NLIIF; NLI-IF |
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SwissProt: |
Q9GZU7 |
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IHC positive control: |
Human breast carcinoma tissue |
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IHC Recommend dilution: |
50-100 |
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WB Predicted band size: |
29 kDa |
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WB Positive control: |
Huvec cells and Hela cells lysates |
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WB Recommended dilution: |
500-3000 |

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