購(gòu)物車
幫助
021-54845833/15800441009
技術(shù)規(guī)格
Background:
This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.
Applications:
WB, IHC
Name of antibody:
PARP1(Cleaved)
Immunogen:
Fusion protein of human PARP1
Full name:
poly(ADP-ribose) polymerase 1
Synonyms:
PARP; PPOL; ADPRT; ARTD1; ADPRT1; PARP-1; ADPRT 1; pADPRT-1
SwissProt:
P09874
IHC positive control:
Human tonsil and Human esophagus cancer; Human thyroid cancer
IHC Recommend dilution:
100-500
WB Predicted band size:
113 kDa
WB Positive control:
293T cell lysate
WB Recommended dilution:
1000-5000
