購物車
幫助
021-54845833/15800441009
技術(shù)規(guī)格
|
Background: |
The TRAF (tumor necrosis factor receptor-associated factor) family of proteins associate with and transduce signals from members of the tumor necrosis factor receptor superfamily. The protein encoded by this gene is found in the cytoplasm and can bind to TRAF1, TRAF2, or TRAF3, thereby inhibiting TRAF function by sequestering the TRAFs in a latent state in the cytoplasm. For example, the protein encoded by this gene can block TRAF2 binding to LMP1, the Epstein-Barr virus transforming protein, and inhibit LMP1-mediated NF-kappa-B activation. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
|
Applications: |
WB, IHC |
|
Name of antibody: |
TANK |
|
Immunogen: |
Fusion protein of human TANK |
|
Full name: |
TRAF family member associated NFKB activator |
|
Synonyms: |
ITRAF; TRAF2; I-TRAF |
|
SwissProt: |
Q92844 |
|
IHC positive control: |
Human colorectal cancer and Human appendix tissue; Human colon tissue |
|
IHC Recommend dilution: |
200-500 |
|
WB Predicted band size: |
48 KD |
|
WB Positive control: |
HepG2, Hela, A549, MCF7 cell lysates |
|
WB Recommended dilution: |
500-2000 |
