購物車
幫助
021-54845833/15800441009
反應種屬： Human
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Background: |
Krueppel-like factor 17 is a protein that in humans is encoded by the KLF17 gene. Transcription repressor that binds to the promoter of target genes and prevents their expression. Acts as a negative regulator of epithelial-mesenchymal transition and metastasis in breast cancer. Specifically binds the 5'-CACCC-3' sequence in the promoter of ID1, a key metastasis regulator in breast cancer, and repress its expression. May be a germ cell-specific transcription factor that plays important roles in spermatid differentiation and oocyte development. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
KLF17 |
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Immunogen: |
Fusion protein of human KLF17 |
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Full name: |
Kruppel-like factor 17 |
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Synonyms： |
ZNF393; Zfp393; RP4-675G8.1 |
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SwissProt: |
Q5JT82 |
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ELISA Recommended dilution: |
2000-5000 |
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IHC positive control: |
Human colon cancer and Human thyroid cancer |
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IHC Recommend dilution: |
25-100 |
